Deep in Mexican ruins, archaeologists discover an ancient culture devoted to snake worship. Their excitement fades when they accidentally unleash a massive, ravenous anaconda that's been dormant for centuries.

A group of world leaders awakens a creature beneath the ocean floor, and mankind's only hope rests on an alliance between the giant ape and his mechanical arch-nemesis.

Dracula, Werewolf, and the Invisible Man must work together to stop Dr. Frankenstein from creating an unstoppable monster.