There is a town in Maine where every story book character you've ever known is trapped between two worlds, victims of a powerful curse. Only one knows the truth and only one can break the spell. Emma Swan is a 28-year-old bail bonds collector who has been supporting herself since she was abandoned as a baby. Things change for her when her son Henry, whom she abandoned years ago, finds her and asks for her help explaining that she is from a different world where she is Snow White's missing daughter.

After their plane crashes into the Amazon River, each member of the Powell family starts to show signs of new, unique and distinct super powers.