Sam Flynn, the tech-savvy and daring son of Kevin Flynn, investigates his father's disappearance and is pulled into The Grid. With the help of a mysterious program named Quorra, Sam quests to stop evil dictator Clu from crossing into the real world.

A runaway train, transporting deadly, toxic chemicals, is barreling down on Stanton, Pennsylvania, and proves to be unstoppable until a veteran engineer and young conductor risk their lives to try and stop it with a switch engine.