Muktha Elsa George was born in a Syro-Malabar Catholic Nasrani family in Kothamangalam near Muvattupuzha, Kerala, India. She is also known as Bhanu. Muktha started her career doing serials in television. She made her debut in the Malayalam film industry through director Lal Jose's Achanurangatha Veedu in which she played the character of Lisamma. Later she started doing Telugu and Tamil films.