An airliner filled with 800 passengers is forced to fly fast and low, above farmlands, suburbs and skyscraper-packed cities or the tons of explosives aboard will detonate. When an elite unit of US Air Force fighter jets is sent to provide escort, they find themselves facing a squadron of unidentifiable warplanes which ignites a deadly air battle that threatens to destroy all life above and below.

Game based on the film of the same name in which the player takes on the role of any member of the Fantastic Four team to go on missions featuring the whole team, or do various solo missions.