The Hotel Del Luna, located in Seoul, is not like any other hotel: its client are all ghosts. Jang Man-Wol, stuck in the hotel for the past millennium, meets Koo Chan-Sung, the new manager.

As a grisly virus rampages a city, a lone man stays locked inside his apartment, digitally cut off from seeking help and desperate to find a way out.

The stories of ambitious career women working at the top of the best portal sites in the IT industry. Paved with wins and losses, their road to success takes a new turn when love comes along the way.

Lee Yool falls off a cliff and nearly dies in an attempted assassination. He loses his memory, and wanders for 100 days under a new name and personality. During this period, he meets Hong Sim, head of the first detective agency in Joseon.

Nam Se-Hee is a single man in his early 30's. He has chosen to not marry. He owns his home, but he owes a lot on his mortgage. Yoon Ji-Ho is a single woman in her early 30's. She does not own a home and envies those that do. She has given up on dating due to her financial struggles. Yoon Ji-Ho begins to live at Nam Se-Hee’s house. They become housemates.

Heo Im is an oriental doctor, acknowledged as the best in acupuncture and moxibustion in Joseon. His success is blocked due to his low status. One day, Heo Im travels though time and finds himself in present day Seoul. He meets Choi Yeon-Kyung. She is doctor firmly believing in only modern medicine.