A private military operation invents futuristic microchip tech that enables the mind of an agent to inhabit the body of another person to carry out covert, deadly missions. But when an agent is killed during a secret mission, his wife takes his place in an attempt to bring the man responsible to justice.

Prince Akeem Joffer is set to become King of Zamunda when he discovers he has a son he never knew about in America – a street savvy Queens native named Lavelle. Honoring his royal father's dying wish to groom this son as the crown prince, Akeem and Semmi set off to America once again.