Forty years after his unforgettable first case in Beverly Hills, Detroit cop Axel Foley returns to do what he does best: solve crimes and cause chaos.

Forensic anthropologist Dr. Temperance "Bones" Brennan and cocky F.B.I. Special Agent Seeley Booth build a team to investigate murders. Quite often, there isn't more to examine than rotten flesh or mere bones.

After being dumped by the girl he believes to be his soulmate, hopeless romantic Tom Hansen reflects on their relationship to try and figure out where things went wrong and how he can win her back.

A brother and sister driving home through isolated countryside for spring break encounter a flesh-eating creature which is in the midst of its ritualistic eating spree.